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中文名:重组人 Glucokinase / GCK 蛋白 品牌:ziqibio
英文名:重组人 Glucokinase / GCK 蛋白 产品编号:Z241020
cas号: 分子式:
规格 价格(RMB) 库存 购买数量 小计 选择
50ug ¥4200.00 1 4200.00
10ug ¥2100.00 2 2100.00

GCK蛋白产品信息

分子别称:GK, GLK, HK4, HHF3, HKIV, HXKP, MODY2, GCK
蛋白构建:A DNA sequence encoding the human glucokinase isoform 1 (NP_000153.1) (Leu 2-Gln 465) was expressed, fused with two additional amino acids (Gly & Pro) at the N-terminus.
分子种属:Human
表达宿主:E. coli
产品状态 & 运输说明:In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

GCK蛋白质控检测

纯度:> 95 % as determined by SDS-PAGE
生物活性:Kinase activity untested
内毒素:Please contact us for more information.
稳定性:Samples are stable for up to twelve months from date of receipt at -70℃
预测N端:Gly
分子量:The recombinant human GCK isoform 1 consists of 466 amino acids and predicts a molecular mass of 52.2 kDa as estimated in SDS-PAGE under reducing conditions.
缓冲液:Lyophilized from sterile 20mM Tris, 10% Glycerol, pH 8.0
1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
2. Please contact us for any concerns or special requirements.

GCK蛋白使用指导

储存方法:Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
复溶条件:A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

产品图片

Human Glucokinase / GCK Protein SDS-PAGE

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参考资料

  • Matschinsky FM. (1990) Glucokinase as glucose sensor and metabolic signal generator in pancreatic beta-cells and hepatocytes. Diabetes. 39(6): 647-52.

  • Magnuson MA, et al. (2004) Glucokinase as a glucose sensor: past, present, and future. Glucokinase And Glycemic Disease: From Basics to Novel Therapeutics (Frontiers in Diabetes). Basel: S. Karger AG (Switzerland). pp. 18-30.

  • Cardenas ML. (2004) Comparative biochemistry of glucokinase. Glucokinase And Glycemic Disease: From Basics to Novel Therapeutics (Frontiers in Diabetes). Basel: S. Karger AG (Switzerland). pp. 31-41.